ConsensusCurrent
KDIGO 2012 — KDIGO Clinical Practice Guideline for Acute Kidney Injury
Kidney Disease: Improving Global Outcomes, 2012
Defines AKI by a rise in serum creatinine of ≥0.3 mg/dL within 48 hours, or ≥1.5x baseline within the prior 7 days, or urine output <0.5 mL/kg/h for ≥6 hours, and stages severity 1-3 by the same criteria. This remains the only final, published KDIGO AKI guideline as of this writing.
Expert opinionModerate certainty
View source guidelineClinical Context & Relevant Topics (2)
Disease ReferenceAcute Kidney Injury in Critical Care
Sepsis-AKI microcirculatory decoupling, KDIGO staging, Furosemide Stress Test (FST), urine microscopy, and the AEIOU dialysis threshold framework.
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Continuous Renal Replacement Therapy (CRRT)
Principles of convection vs diffusion, filtration fraction, delivered effluent dosing (20–25 mL/kg/h), Regional Citrate Anticoagulation, and citrate toxicity.
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