Corrected Sodium (Hyperglycemia)
Estimates true serum sodium in the setting of hyperglycemia, which dilutes measured sodium by drawing water into the vascular space.
Formula
Corrected Na = Measured Na + 1.6 × (Glucose − 100) / 100
Result
Enter all values to see the result.
Limitations
- This calculator uses the traditional correction factor of 1.6 mEq/L per 100 mg/dL of glucose above 100 mg/dL; some evidence supports a larger factor (2.4) at very high glucose levels, which would produce a higher corrected value than shown here.
- Below a glucose of roughly 100 mg/dL, the correction term becomes negative — this formula is intended for hyperglycemia and is not meaningful in hypoglycemia.
- Does not account for other osmotically active substances (e.g. mannitol) that can similarly dilute measured sodium.
References
- Katz MA. Hyperglycemia-induced hyponatremia — calculation of expected serum sodium depletion. NEJM 1973.
Clinical Context & Relevant Topics (3)
Disease ReferenceTonicity assessment, etiologic classification, 3% hypertonic saline bolus protocols, individualized ODS-safe correction limits, DDAVP relowering, DI diagnostics, and evidence-aware hypernatremia correction.
Pathophysiology, SGLT2i euglycemic DKA, balanced fluid resuscitation, potassium-before-insulin safety rules, dextrose addition kinetics, and subcutaneous transition.
Sepsis-AKI microcirculatory decoupling, KDIGO staging, Furosemide Stress Test (FST), urine microscopy, and the AEIOU dialysis threshold framework.
Relevant Clinical Pathways (9)
Decision ProtocolsFrom urgent 'AEIOU' indication screening and modality selection to vascular access, dosing, and anticoagulation.
From emergent cardiac membrane stabilization to intracellular shifting, elimination, and dialysis triggers.