RecentRCT

Takotsubo exercise/CBT recovery

Physical Exercise or Cognitive Behavioral Therapy for Takotsubo Cardiomyopathy: A Randomized Controlled Trial.

Circulation. Heart failure, 2025 · Multicenter randomized trial

Population: 76 participants, mostly women
Intervention: 12-week exercise or CBT
Comparator: Standard care
Primary outcome: Resting myocardial phosphocreatine/ATP ratio
Result: Energetics and exercise measures improved; no significant symptom/strain improvement.

What the trial found

Energetics and exercise measures improved; no significant symptom/strain improvement.

Clinical interpretation

Recovery physiology study; no acute shock or mortality conclusion.

Moderate certainty

Clinical Context & Relevant Topics (1)

Disease Reference

Transient stress-associated ventricular dysfunction that can mimic ACS and cause pulmonary edema, arrhythmia, LVOTO, thrombus, or cardiogenic shock.