RecentRCT

Tele-Rehab

Integrated Telehealth Rehabilitation and Quality of Life in Mechanically Ventilated Adults: A Randomized Clinical Trial.

JAMA, 2026 · Stepped-wedge cluster randomized trial

Population: 1,916 acute-hypoxemic-failure adults in 20 Brazilian hospitals
Intervention: Integrated ICU/ward/home telehealth rehabilitation
Comparator: Usual care
Primary outcome: 90-day postdischarge EQ-5D-3L utility, including death as zero
Result: Adjusted utility difference 0.049 (95% CI 0.0002–0.098), P=.04; no significant survivor-utility difference.

What the trial found

Adjusted utility difference 0.049 (95% CI 0.0002–0.098), P=.04; no significant survivor-utility difference.

Clinical interpretation

High mortality and cluster/time design constrain extrapolation and component attribution. Overall utility benefit does not imply improved utility among survivors.

Moderate certainty

Clinical Context & Relevant Topics (1)

Disease Reference

Post-ICU Syndrome, Survivorship & Rehabilitation

Prevention, recognition and follow-up of physical, cognitive and psychological morbidity after critical illness, including ICU-acquired weakness and family impact.

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