ICU Map
hematology / oncology

Cancer Patient with Abrupt Electrolyte Collapse

Hyperkalemia, hyperphosphatemia, hypocalcemia and AKI around cancer therapy.

Recognize

  • High tumor burden, rapidly proliferative or treatment-sensitive malignancy, high LDH, renal dysfunction and elevated baseline urate increase risk; spontaneous TLS can occur.

Act

  • High-risk patients need frequent laboratory reassessment and cardiac monitoring because hyperkalemia and hypocalcemia-related arrhythmias may evolve rapidly.

Reassess

  • Reassess trajectory, organ support, competing diagnoses and failure of first-line therapy; escalate early when physiology is worsening.

Evidence status

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Actionable Clinical Workflows (1)

Step-by-step ICU Processes
Tumor Lysis Syndrome — ICU Decision Pathway

Prevention and ICU treatment of tumor lysis syndrome with electrolyte emergencies, urate control, AKI prevention and timely dialysis.

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Deep-Dive Topic Destinations (1)

Reference Knowledge
Tumor Lysis Syndromehematology

Risk-stratified prevention and ICU treatment of tumor lysis syndrome with hyperkalemia, hyperphosphatemia, hypocalcemia, hyperuricemia and AKI.

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