ConsensusCurrent

US TLS Consensus 2023 — Expert consensus guidelines for the prophylaxis and management of tumor lysis syndrome in the United States

United States Tumor Lysis Syndrome Expert Delphi Panel, 2023

Risk-stratify TLS before cytotoxic or targeted therapy, use hydration and risk-appropriate urate-lowering therapy, monitor electrolytes and kidney function closely, and escalate urgently for life-threatening potassium, phosphate, calcium, urate or renal complications.

Expert opinionLow certainty

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Clinical Context & Relevant Topics (1)

Disease Reference

Tumor Lysis Syndrome

Risk-stratified prevention and ICU treatment of tumor lysis syndrome with hyperkalemia, hyperphosphatemia, hypocalcemia, hyperuricemia and AKI.

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