GuidelineCurrent

SSC 2026 — Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026

Society of Critical Care Medicine / European Society of Intensive Care Medicine, 2026

Recommend antimicrobial de-escalation once a microbiological diagnosis and susceptibility results are available; suggest de-escalation when no pathogen is identified on final cultures and the patient is improving.

Strong recommendationVery low certainty

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Clinical Context & Relevant Topics (1)

Disease Reference

Sepsis

Life-threatening organ dysfunction caused by a dysregulated host response to infection — recognized by an acute rise in SOFA score, not by infection plus fever alone.

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