GuidelineCurrent

SCCS/SSAI Ketamine RPG 2025 — Ketamine Analgo-sedation for Mechanically Ventilated Critically Ill Adults: A Rapid Practice Guideline

Saudi Critical Care Society / Scandinavian Society of Anaesthesiology and Intensive Care Medicine, 2025

Conditionally suggests against ketamine monotherapy for routine ICU analgo-sedation when other agents are available; adjunct ketamine or usual non-ketamine sedation are both acceptable individualized approaches, with very low certainty for many outcomes.

Conditional recommendationVery low certainty

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Clinical Context & Relevant Topics (1)

Disease Reference

ICU Sedation, Analgesia, Delirium & Liberation

Analgesia-first sedation, light sedation targets, ABCDEF bundle, spontaneous breathing trials, and non-pharmacologic delirium mitigation.

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