GuidelineHistorical / Foundational
ATA — Guidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement
American Thyroid Association, 2014
For myxedema coma, initiate IV levothyroxine with cardiac-risk dose adjustment and give empiric stress-dose glucocorticoids first. Liothyronine is optional with caution. The specific recommendations rest on low-quality evidence; see the separate 2026 joint consensus for newer emergency guidance.
Strong recommendationLow certainty
View source guidelineClinical Context & Relevant Topics (2)
Disease ReferenceMyxedema Coma
Recognition and ICU treatment of decompensated profound hypothyroidism with altered mental status and multiorgan dysfunction.
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Endocrine Emergencies in Critical Care
Bedside recognition and organ-support priorities for thyroid storm, myxedema coma, adrenal crisis, pheochromocytoma crisis, and severe hypercalcemia.
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