GuidelineCurrent
ERS 2022 — ERS Clinical Practice Guidelines: High-Flow Nasal Cannula in Acute Respiratory Failure
European Respiratory Society, 2022
Suggest HFNC over conventional oxygen therapy in hypoxemic acute respiratory failure; suggest HFNC over noninvasive ventilation in hypoxemic acute respiratory failure; suggest HFNC over conventional oxygen during breaks from NIV. All conditional recommendations.
Conditional recommendationLow certainty
View source guidelineClinical Context & Relevant Topics (2)
Disease ReferenceHypoxemic Respiratory Failure
Pathophysiologic mechanisms (shunt vs V/Q mismatch), dynamic ROX index trajectories, P-SILI prevention, and evidence-based oxygen escalation ladders.
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Respiratory Failure: Basic Principles
Core taxonomy (Types I–IV), alveolar gas exchange physiology, work-of-breathing mechanics, and escalation thresholds in acute respiratory failure.
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