GuidelineCurrent

Adult HLH 2019 — Recommendations for the Management of Hemophagocytic Lymphohistiocytosis in Adults

Histiocyte Society / International Expert Group, 2019

Adult HLH requires rapid recognition of the hyperinflammatory syndrome, simultaneous trigger investigation, organ support, and early hematology-directed immunomodulatory therapy tailored to severity and cause.

Conditional recommendationModerate certainty

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Clinical Context & Relevant Topics (1)

Disease Reference

HLH / Macrophage Activation Syndrome

Adult ICU recognition, trigger investigation and individualized treatment of hemophagocytic lymphohistiocytosis/macrophage activation syndrome.

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