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ASH 2018 — American Society of Hematology 2018 Guidelines for Management of Venous Thromboembolism: Heparin-Induced Thrombocytopenia

American Society of Hematology, 2018

Use the 4Ts score (not gestalt) to estimate pretest probability of HIT. For intermediate/high-probability scores, obtain a PF4 immunoassay. Discontinue heparin and start a non-heparin anticoagulant for intermediate/high-probability suspected or confirmed HIT, at an intensity guided by bleeding risk when no other indication for therapeutic anticoagulation exists.

Strong recommendationModerate certainty
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