ConsensusCurrent
Digoxin Toxicity Consensus 2025 — Expert Consensus on the Diagnosis and Management of Digoxin Toxicity
Multidisciplinary Expert Consensus, 2025
Recognize acute versus chronic exposure and administer digoxin-specific immune Fab for life-threatening digoxin toxicity; extracorporeal removal is not a substitute for Fab in severe poisoning.
Expert opinionLow certainty
View source guidelineClinical Context & Relevant Topics (2)
Disease ReferenceToxicologic Emergencies in Critical Care
Resuscitate first, identify toxidromes and ECG/acid-base threats, use toxin-specific antidotes, and escalate early to poison-center, extracorporeal, or ECLS support when physiology demands it.
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Severe Hyperkalemia in Critical Illness
Nernst resting potential mechanics, ECG progression, the 3-step resuscitation framework (Stabilize, Shift, Eliminate), and post-dialysis rebound kinetics.
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