AGA — AGA Clinical Practice Update on Management of Clostridioides difficile Infection in Adults: Expert Review

Fulminant CDI requires multidisciplinary care, enteral high-dose vancomycin with IV metronidazole and rectal vancomycin when ileus limits delivery. Consider conventional multi-dose FMT in selected fulminant disease; approved recurrence-prevention microbiota products have not been established for acute fulminant treatment. This is ungraded expert advice.