GuidelineCurrent

Anaphylaxis 2023 — Anaphylaxis: A 2023 Practice Parameter Update

AAAAI/ACAAI Joint Task Force, 2023

Intramuscular epinephrine is first-line treatment for anaphylaxis and should not be delayed for antihistamines or corticosteroids; refractory shock requires repeated epinephrine, fluids, airway planning, and escalation to monitored vasoactive support.

Conditional recommendationModerate certainty

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Clinical Context & Relevant Topics (1)

Disease Reference

Anaphylaxis & Refractory Anaphylactic Shock

Immediate epinephrine-first management of airway edema, bronchospasm, vasoplegia and refractory anaphylactic shock in the ICU.

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