AHA/ASA 2019 — Guidelines for the Early Management of Patients With Acute Ischemic Stroke

This guideline has been superseded by a newer recommendation. Check the Knowledge Map or the current topic page for the guideline that replaces it.

IV alteplase/tenecteplase is recommended within 4.5 hours of symptom onset (target BP < 185/110 mmHg). Endovascular thrombectomy is indicated within 6 hours for anterior circulation LVO and up to 24 hours in selected patients meeting DAWN or DEFUSE-3 perfusion imaging criteria.