GuidelineCurrent
AHA Toxicology 2025 — Part 10: Adult and Pediatric Special Circumstances of Resuscitation: 2025 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care
American Heart Association, 2025
Life-threatening poisoning requires toxin-specific resuscitation in addition to standard life support. The 2025 AHA guidance includes recommendations for opioid toxicity, organophosphate/carbamate poisoning, cyanide, digoxin, sodium-channel blockers, calcium-channel blockers, beta-blockers, local anesthetic toxicity and other critical poisonings.
Conditional recommendationModerate certainty
View source guidelineClinical Context & Relevant Topics (2)
Disease ReferenceTricyclic & Sodium-Channel Blocker Toxicity
Recognition and resuscitation of sodium-channel blocker poisoning with seizures, QRS widening, ventricular dysrhythmia and shock.
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Toxicologic Emergencies in Critical Care
Resuscitate first, identify toxidromes and ECG/acid-base threats, use toxin-specific antidotes, and escalate early to poison-center, extracorporeal, or ECLS support when physiology demands it.
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