ConsensusCurrent

APASL global ACLF consensus — The Global ACLF Consensus : the 'Istanbul Document'

APASL global ACLF consensus, 2026

The Istanbul document proposes Type-A and Type-B ACLF phenotypes with liver-failure core criteria. Keep this framework distinct from existing EASL-CLIF/NACSELD definitions; consensus harmonization does not mean all previous study populations or prognostic scores are interchangeable.

Expert opinionLow certainty

View source guideline

Clinical Context & Relevant Topics (1)

Disease Reference

Decompensated Cirrhosis & ACLF

Recognition and organ-support of decompensated cirrhosis and acute-on-chronic liver failure, including bleeding, infection, encephalopathy and transplant triage

View Topic Context →