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Meta-Analysis

Antibiotic prophylaxis for cirrhotic patients with gastrointestinal bleeding

Chavez-Tapia NC, Barrientos-Gutierrez T, Tellez-Avila F, et al., 2010 · 12 studies included

Summary

Cochrane review of 12 randomized trials (n=1,241) of short-term antibiotic prophylaxis in cirrhotic patients with GI bleeding.

Conclusion

Antibiotic prophylaxis significantly reduced all-cause mortality (RR 0.79; 95% CI, 0.63 to 0.98), bacterial infections, and rebleeding.

High certainty