Adjunctive corticosteroids in herpes simplex virus encephalitis: a meta-analysis of randomized and observational studies.
Zhang et al., 2026 · 4 studies included
Summary
209 patients: two randomized trials plus two retrospective studies, analyzed separately.
Conclusion
Randomized estimates were imprecise and neutral; observational confounding and inconsistent effects preclude routine efficacy claims or certainty about life-threatening edema.