Meta-Analysis

Resting-State Functional MRI and Clinical Outcomes After Acute Disorders of Consciousness: A Systematic Review.

Kazazian et al., 2026 · 30 studies included

Summary

800 patients in 30 heterogeneous acute-disorders-of-consciousness studies; network measures were associated with later outcomes.

Conclusion

Small heterogeneous studies do not validate standalone individual prognosis or awareness/BD-DNC determination.

Low certainty

Clinical Context & Relevant Topics (1)

Disease Reference

Altered Consciousness, Coma, & Delirium in the ICU

ARAS neuroanatomy, structural vs toxic-metabolic coma, the comprehensive Coma Exam (pupils, cold calorics, posturing), FOUR score, and CAM-ICU delirium.

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