Noninvasive Ventilation in Acute Asthma Exacerbations: A Systematic Review.
Homer-Bouthiette C et al., 2025 · 13 studies included
Summary
Eight RCTs and five observational studies evaluated NIV added to standard treatment in adults with acute asthma.
Conclusion
The RCT intubation estimate was imprecise (RR 0.46, 95% CI 0.16–1.29); mortality could not be assessed reliably. Evidence was low/very low certainty. A carefully monitored NIV trial may be reasonable in selected patients; no established survival benefit or justification for delaying intubation.