endocrine

Myxedema Coma vs Euthyroid Sick Syndrome

Thyroid Emergencies

Myxedema Coma vs Euthyroid Sick Syndrome
Feature	Myxedema Coma	Euthyroid Sick Syndrome
Mechanism
TSH	Markedly elevated (primary) or low (secondary)	Normal or mildly low (often transiently suppressed)
rT3	Normal	HIGH (T4 → rT3 shunting)
Treatment	IV levothyroxine loading + hydrocortisone	Treat underlying illness; do NOT give thyroid hormone

Comparing: Myxedema Coma

Markedly elevated (primary) or low (secondary)

Normal

IV levothyroxine loading + hydrocortisone

For healthcare-professional education. Clinical decisions require patient-specific assessment and local protocols.